Posts Tagged ‘IBD (COLITIS/ CROHN’S) STUDY’

Northport Crohn’s & Colitis Study Underway

Northport 2016 BWH/Harvard

Crohn’s & Colitis Study Underway

~ Still Recruiting Participants ~

 

Dr. Josh Korzenik, The Director of the Crohn’s and Colitis Center at Brigham and Women’s Hospital (BWH), one of the leading IBD researchers in the country, and his team have begun their second study of the health cluster of ulcerative colitis and Crohn’s disease diagnosed in Northport residents.  Their 2011 study concluded diagnosed cases of ulcerative colitis or Crohn’s disease in the community was 10 to 15 times higher than national standards. This was one of the largest health clusters of these illnesses Dr. Korzenik  has ever seen.

The current study is a more in-depth epidemiological case-control study.  The focus is in finding a possible correlation of chronic exposure to specific heavy metals and ulcerative colitis and Crohn’s disease.

The case-control study includes participants who have been diagnosed with either Crohn’s or colitis as well as participants who have not been affected.  In March I asked for volunteers for this new study. The response I received was overwhelming. I provided the full list to Dr. Korzenick, however if you volunteered and have still not heard from them please call or e-mail them at:  IBDresearch@bwh.harvard.edu  or  617-732-9173.

It is not too late to volunteer if you haven’t.  They are still recruiting participants.

The scope of this study, and the study itself, has the very likely possibility of providing groundbreaking information the scientific community is greatly lacking.

Thank you to the many past and present Northport residents who have volunteered to participate in this study.

We cannot change the past or the damage Teck’s pollution has caused, and continues to cause, to countless Northport residents. However, by participating in studies like this invaluable information on the routes and duration of exposure to specific environmental toxins have in triggering or causing these rare diseases.  This could help accomplish prevention, regulatory changes, and better treatment options and cures for Crohn’s disease, ulcerative colitis, and possibly many other autoimmune diseases.

–  Jamie Paparich

BWH/Harvard Northport IBD Study to begin next month

2016 BWH/Harvard Crohn’s & Ulcerative Colitis study to begin in November

In 2011  Dr. Josh Korzenik, The Director of the Crohn’s and Colitis Center at Brigham and Women’s Hospital (BWH), one of the leading IBD researchers in the country, and his team conducted a study of Northport residents through health questionnaires and medical record confirmations. He discovered a health cluster of Northport residents with either ulcerative colitis or Crohn’s disease that was 10 to 15 times higher than national standards. This was one of the largest health clusters of these illnesses he has ever seen.

The causes, and a cure, for ulcerative colitis and Crohn’s disease have long baffled the scientific community.  Northport’s historical exposure to specific heavy metal toxins may be a contributing factor to the abnormally high number of residents with ulcerative colitis and Crohn’s disease.

Dr. Korzenik is moving forward next month with a new epidemiological case-control study of Northport residents; focusing on a possible correlation to chronic exposure to heavy metals triggering ulcerative colitis and Crohn’s disease.

In March I asked for volunteers for this new study. Participants needed are residents diagnosed with either Crohn’s or Colitis, as well as residents who do not have either of these illnesses (a control group).  I received many volunteers to participate.  Thank you!   However, I do not want to miss anyone who may want to participate in this ground breaking study.

If you have not already contacted me* to volunteer and you are willing to participate in this study, both diagnosed residents and non diagnosed residents, please e-mail me as soon as possible.  The study begins in the next two weeks.  

Contact Info:  jamie_paparich@hotmail.com   or  northportproject@hotmail.com

* If you are not sure if you contacted me already please feel free to e-mail again!

The study is simple, and will take only a few minutes of your time.  You will be contacted by the research team, either by telephone or e-mail depending on your preference, to give your consent to participate in the study.  A questionnaire and a kit including scissors and nail clippers to obtain hair and nail samples will be sent to your home.  You will then send the packet back to the researchers, and the assays will be done at their lab.

Thank you so much to the community for your amazing support in volunteering for this much needed study!

 

Contact Info:  jamie_paparich@hotmail.com   or  northportproject@hotmail.com

Linking Air Pollution to Colitis & Crohn’s

Linking Air Pollution to Ulcerative Colitis and Crohn’s Disease;                      

A statement for Northport residents, epidemiologists, research organizations and universities on an opportunity for an epidemiological case-control study on Crohn’s and Ulcerative Colitis that continues to be ignored

By Jamie Paparich

Extensive studies continue to be done on human health issues linked to exposure to air pollution. It is well documented that exposure to air pollution has been a contributing factor in multiple forms of lung and heart diseases.

However, almost no studies have been done on the effects of air pollution on the gastrointestinal tract, specifically the intestines. Even though the bodies intestines absorb the majority of the toxins inhaled and ingested from air pollution.

Crohn’s Disease and Ulcerative Colitis are the two known inflammatory bowel diseases (IBD). Crohn’s disease can cause inflammation throughout the entire GI tract, anywhere from the mouth to the anus. It most commonly effects the small intestines, causing chronic inflammation of the lining of the small intestines.  Ulcerative colitis impacts the large intestine/colon.  Colitis causes inflammation and open sores, or ulcers on the lining of the large intestine/colon. Both Crohn’s and Colitis causes severe abdominal discomfort and frequent emptying of the colon. These diseases are incurable and impacts not only the patients long term health, but also their quality of life. The scientific and medical community have been unable to discover what causes these rare diseases, which limits the treatment options.

AIR POLLUTION

Depending on where you are, air pollution can contain anything from fire smoke, ash, emissions from smelters, mining operations, power plants, construction sites, road construction, and automobiles…just to name a few. All air pollution contains particulate matter (PM). Particulate matter is liquid and solid particles suspended in the air that contains a mixture of the toxic pollution, the dust and pollen in your air.  The particulate matter is how the toxins from pollution enter the body. 

Exposure

Inhalation & Dermal:

There are two sizes of particulate matter.

– PM 10:  10 microns (a millionth of a meter) in diameter or less. These are small enough to be inhaled and accumulate in the respiratory system. Many of the particles pass from the respiratory system through mucus down the GI Tract.

– PM 2.5:  2.5 microns in diameter (1/10,000 of an inch). These are so small they are inhaled into the respiratory system, but then are able to pass through the lungs into the bloodstream, and also from the respiratory tract through the GI Tract. These size particles can also be absorbed through the skin.

Ingestion:

The particulate matter falls onto gardens, crops, the food animals ingest, water sources, and the water ways fish inhabit. In turn, we ingest the PM through those products when consumed.

NORTHPORT AIR POLLUTION

In the case of Northport, air monitoring has shown that our air contains dangerous levels (way above safety standards) of arsenic and cadmium.  This is from the emissions released from the smoke stack at Teck Resource, a Canadian smelter located 3 miles upriver. The particulate matter in our pollution contains several heavy metals, not just arsenic and cadmium, because of the smelters emissions. 

BODIES REACTION

Gastrointestinal Tract

    • Inhalation:  Once particulate matter is inhaled into the respiratory tract, it is sent through the GI tract through mucocilliary clearance, eventually entering the intestines.  The majority of the  particulate matter inhaled into the body will end up in the intestines.  Not all of these toxins are expelled from the body. Many are absorbed and accumulate into the intestinal walls. This induces systemic effects; directly effecting the epithelial cells (the barrier between toxic invaders and healthy cells lining the intestine). System inflammation then triggers immune activation.  Over time, this leads to the immune system turning on the bodies good cells as well.
    • Ingestion:  Food and water containing PM toxins are ingested into the stomach, then passed to the intestines, where the toxins will, once again, spend the longest amount of time in the body, before being expelled from the body. The toxins not expelled will also inducing systemic effects, system inflammation, and eventually immune over stimulation.

IMMUNE SYSTEM & BIO-TOXICITY

Particulate matter alters the body’s immune system reaction. The immune system discovers and destroys disease causing organisms, viruses, and foreign agents in our bodies. The immune system kicks into overdrive due to the ingestion and inhalation of particulate matter, especially containing heavy metals. Eventually the chronic, overstimulation of the immune systems will cause chronic inflammation throughout the body, or to specific organs. 

Exposure to high levels of heavy metals is an obvious concern.  However, the more dangerous type of exposure is long term exposure, even to low levels.  This type of exposure causes the heavy metals to slowly accumulate in the bodies organs, causing biotoxic effects.  According to the research published in Heavy metal pollution and human biotoxic effects, (Duruibe, J. O. 1 *, Ogwuegbu, M. O. C. 2 and Egwurugwu, J. N. 3),  “….(G)eneral signs associated with biotoxicity of (sic) cadmium, lead, arsenic, mercury, zinc, copper and aluminum poisoning:  gastrointestinal (GI) disorders….”

INFLAMMATORY BOWEL DISEASE

In people with IBD, the immune system attacks the heavy metal toxins in the intestines.  Because of the accumulation of heavy metals toxins, from chronic exposure to specific air pollution, some individuals immune systems go haywire, attacking the toxins and healthy cells.  This eventually leads to chronic-inflammation, ulcerations, and thickening of the intestinal wall.  The result of this is Crohn’s disease or Ulcerative Colitis, and likely several other auto immune health issues.

However, not all people exposed to the same level of specific heavy metal toxins will develop Crohn’s or Colitis.  When the first cluster of Northport residents with either Ulcerative colitis or Crohn’s disease was discovered in 1992 statistically 1 in 100,000 people in the U.S. were diagnosed with one of these IBDs.  In 1992 Northport’s population was approximately 375 people, and 15 residents had been diagnosed with either Crohn’s or Colitis.  In 2012 a research team from Massachusetts General Hospital’s Crohn’s and Colitis Center conducted an IBD study of Northport and confirmed 17 people had either Crohn’s or Colitis, the population in 2012 was still around 375 people.  This is 11.5 to 15 times higher than the national standard. 

In 1992 and 2012’s study the residents diagnosed with either Crohn’s or Colitis lived within a two mile radius of each other, in the Columbia River Valley.  This valley was nicknamed “The Heavy Fallout Zone” by the EPA, due to the high levels of heavy metal toxins found in their sampling.  The levels were so elevated in this area because Teck’s air emissions, full of heavy metal toxins and sulfer dioxide, would flow north down the river and become trapped in the valley.  There is would settle, the particulate matter falling onto every surface below it, and being inhaled by the residents living on the little farms scattered along the banks of the river. These residents were chronically exposed to the dangerously high levels of arsenic and cadmium in the air for decades. 

However, the question still remains.  Why did some of these residents, living in the “heavy fallout zone”, contract Colitis or Crohn’s and some didn’t.  It impacted the children who grew up in the area the most, but not all of the children.  In the study; Exposure to ingested airborne pollutant particulate matter increases mucosal exposure to bacteria and induces early onset of inflammation in neonatal IL-10-deficient mice, (Salim SY1, Jovel J, Wine E, Kaplan GG, Vincent R, Thiesen A, Barkema HW, Madsen KL), the research team aimed to determine if exposure to particulate matter during the neonatal period and early-life would alter colitis in a mouse model.  The team concluded “Our data suggest that early exposure to pollution particulates can result in an earlier onset of intestinal disease in genetically susceptible hosts and can alter responses to gut injury in later life.”

Scientist have not been able to discover an inheritance/genetic pattern to IBDs.  Most scientists and researchers whose work is focused on Inflammatory Bowel Diseases and the GI Tract believe both genetic and environmental factors trigger the illnesses. 

Science Director of the Science and Environmental Health Network (SEHN) , Ted Schettler, M.D., M.P.H., shared his thoughts about the high occurrence of these diseases in our area; “If it is in anyway related to smelter emissions I’d wonder about changes in the intestinal micro biome as a plausible mechanism that could link metal exposure to inflammatory bowel disease.”

EPIDEMIOLOGY CASE-CONTROL STUDY

The community of Northport exceed all of the requirements to conduct an accurate epidemiological case-control study of the contribution chronic exposure to specific heavy metal toxins in air pollution has on triggering inflammatory bowel disease, as well as the impact it may specifically have on the immune system response.

The EPA is currently conducting a Human Health Risk Assessment of the area, as part of their agreement with Teck Resources in conducting remedial investigations and feasibility studies of the Upper Columbia River area and Northport. The EPA, nor Teck have any plans to monitor our air in any of the investigations or assessments.  The EPA has no interest in looking at the cluster of diagnosed cases of Crohn’s or Colitis in the area, spanning three generations. 

Today members of the community continue to be diagnosed with Crohn’s or Colitis, and more will continue to be diagnosed until something is done. 

Disease cluster in town of Northport, Washington linked to pollutants released by smelter in British Columbia

By Kraft Palmer Davies, PLLC

Harvard Medical School researchers have determined Northport, Washington, a tiny 296-resident border town, has 10 to 15 times the normal rates of the inflammatory bowel disease. The town is located downwind and downriver of a smelter in Trail, British Columbia run by Teck Resources, which for nearly a century funneled pollution through the narrow canyon of the Columbia River. Residents have long suspected a link between pollution from the smelter and their high incidence of inflammatory bowel disease.

For nearly a century, the Canadian smelter pumped slag, a byproduct of metals refining, directly into the river. More than 10 million tons of the granular slag created the “black sand” beaches of the upper Columbia, a 150-mile reach of the river between the Canadian border and Grand Coulee Dam. The slag contains 25 compounds that include lead, arsenic, cadmium and mercury. Liquid mercury and other metals also flowed from the smelter’s sewer systems into the river. More pollutants came out of the plant’s smokestacks.

In the 1980s, the state placed air monitors in Northport which detected elevated levels of arsenic and cadmium. In the early 1990s, anglers in the upper Columbia River reported seeing beads of liquid mercury floating in the water. “When we were kids walking to school, we could smell it in the air,” said a 56-year-old resident of Northport who grew up about 15 miles from the smelter’s stacks.

About 1.4 million people nationwide have ulcerative colitis or Crohn’s disease, a similar inflammatory bowel condition. The illnesses affect about one in every 200 people. Both diseases are believed to have environmental triggers, but despite extensive research the causes have never been identified. Researchers are now looking to Northport for clues.

Last year, 119 current and former Northport residents took part in a health survey designed by Dr. Josh Korzenik.. Seventeen had confirmed cases of either ulcerative colitis or Crohn’s disease. “That’s about 10 to 15 times what we’d expect to see in a population the size of Northport,” said Korzenik, director of the Crohn’s and Colitis Center at Brigham and Women’s Hospital, one of Harvard Medical School’s teaching hospitals. “I’m not aware of any other cluster like it.”

Researchers have long suspected that environmental toxins play a role in Crohn’s disease and colitis, which have symptoms including abdominal pain and diarrhea. Both illnesses emerged after the Industrial Revolution, when exposure to pollution from coal-fired factories and vehicle emissions became a part of many people’s daily lives.

Korzenik has ruled out a genetic influence in the town’s cluster: Few of the individuals were related. Seven of the 17 cases were people who lived along Mitchell Road, where sulfur dioxide emissions from the smelter killed farmers’ crops in the 1920s and 1930s, leading to an international lawsuit. Korzenik plans to expand his research to nearby communities.

Residents of Washington living along the upper Columbia River suffering from inflammatory bowel disease may be entitled to recover from Teck and/or affiliated corporations for their injuries.

Trail B.C. community requests colitis/crohn’s study in wake of results of recent Harvard study of Northport residents

link to article

Trail Seeks Updated Info On Bowel Disease Risks

20121120-112826.jpg

Monday, November 19, 2012 – 7:46 AM

Trial has asked the Ministry of Health for updated information regarding the local risks of diseases like Crone’s and Colitis.

Mayor Dieter Bogs says a study completed in 1994 did not show a greater chance. But a September analysis by the Harvard Medical School indicated that Northport Washington residents downstream from the Teck Smelter are seeing increased incidences of 10-to-15 times the normal rate.

Council will send a letter to the Ministry of Health as a result and Bogs doesn’t expect the update to take too long because they are just updating old information and not conducting a new study.

Teck has previously said a number of human health studies show no link between the Trail operations and the diseases.

Huge Admission from Canadian Cross-Border Polluter, Teck Resources

Huge Admission from Canadian Cross-Border Polluter, Teck Resources

By rosehips | Posted September 11, 2012 | Northport, Washington

I have personally been waiting decades for this. In an historic admission on the eve of a court case pitting two members of the Colville Confederated Tribes, the state of Washington and the EPA against a Canadian company with a long history of pollution into the Columbia River, the polluting company has admitted that their toxic discharges have crossed the border into Washington State.

Teck Resources (fka Teck Cominco) is located just north of the Canadian border and is one of the biggest lead/zinc smelters in the world. They have been operating the smelter for over 100 years. A byproduct of the smelting process is black slag, which Teck discharged directly into the river for decades until locals across the border in the Northport, WA area began protesting back in the early 1990’s. This pressure helped prompt the Canadian government to force regulations upon the company. They built a brand new smelter. When the smelter design was discovered to be flawed, they built another one. They stopped dumping slag. We won that victory, but the fight didn’t end there.

For decades Teck maintained that the black slag discharged into the Columbia, that by some estimates totals over 50 million tons, was inert. But then in the 1990’s it was proven that the slag is not inert. The toxins within the vitrified sand are bio-available over time. And time has had it’s way with the slag.

In 1999, members of the Colville Confederated Tribes (CCT) came to local activists in the Northport area and asked for help in making Teck accountable for their pollution. Through years of tough legal work, years of study have been conducted by Teck, after an agreement with tribal members, the EPA and the state of Washington was reached. As local citizens directly impacted by the discharges, members of Citizens for a Clean Columbia (CCC) have worked hand in hand with the CCT, the EPA and various state agencies to see this day come. Teck has now admitted some of their toxic discharges that they released wound up in Washington. This sets the stage for them to be held accountable for the damages.

The locals in the Northport area, where I lived for 18 years, have been screaming for an epidemiological study for decades to prove what we already know: that there is a cluster of intestinal bowel diseases (IBD) in the area. We have asked the state to answer the question: Why do so many Northport residents have colitis and Chrohn’s disease? Well, after more than one flawed study, we finally got the study we were looking for. A team out of Massachusetts came out and surveyed residents. They analyzed the data and they confirmed that there is indeed a cluster of IBD’s with rates 15 times greater than in the general public.

So now what? I guess we will see what the courts determine. Attorneys have already been flocking, waiting to represent local citizens who have been impacted by Teck Resources. It is going to be an interesting phase of our fight for justice for the people who live along the upper Columbia River.

Stay tuned for updates.

Read more from the Globe and Mail:

http://www.theglobeandmail.com/globe-investor/teck-admits-operations-polluted-us-waters/article4533432/?cmpid=rss1

Photos of “Black Sand Beach” by me. (Sorry they got pixelated!) The beach was remediated a few years ago by Teck at a considerable expense. They replaced the black slag that give the beach its name with clean sand. It was a major job but was necessary to protect to local folk who swim and fish there.

Thanks for reading!

Northport, the Town That Could Help Cure IBD

Northport, the Town That Could Help Cure IBD

Published September 18, 2012
Written by Jaime Weinstein

Small towns are often known for having a story or legend to call their own. This story in particular involves the quiet little town of Northport, Wash., a long-standing pollution battle with a Canadian mining company, and a potential cluster of Inflammatory Bowel Disease diagnoses. For the 295 residents who live in and around Northport, this story is one they definitely could do without.

The Cast

Canadian mining company Teck Resources Ltd. (formerly Teck Cominco) one of the biggest lead and Zinc smelters in the world has a history of pollution dating back close to a century.

Inflammatory Bowel Disease, which includes Crohn’s disease and ulcerative colitis; cause of disease is currently unknown, but researchers believe that genetic and environmental factors are associated

A courageous former Northport resident, Jamie Paparich, who brings information of 50 current and past residents with IBD to the attention of Harvard researchers in 2011.

117 current and former Northport residents who participate in a health study designed by Dr. Joshua Korzenik, a Harvard researcher and director of Crohn’s and Colitis Center at Brigham and Women’s Hospital.

The 17 people in Dr. Korzenik’s initial study who came back with confirmed cases of either type of IBD

The Plot

In the early 1900s, the company now known as Teck Resources Ltd. started out as a gold mine operation along the Columbia River in Trail B.C., Canada. As the years moved on the mining operation grew to include Zinc, copper, coal and oil.

Starting in the 1930s, farmers from the towns of Northport and Marcus file suit against Teck Cominco (the company’s name at the time) on the grounds that the smelter’s air pollution is destroying crops, especially along farms located on Mitchel Road. This became a landmark case in terms of farmers and pollution.

By 1940, the mining company admits to dumping up to 1,000 tons of slag (mining waste consisting of harmful chemicals like arsenic, cadmium and lead). By the 1980s mercury spills and regular dumping are added to the list of pollutants the company’s smelter is responsible for.

A smelter is a machine that uses extreme heat and pressure to melt or fuse ore in order to separate metallic compounds. The extraction process creates extreme amounts of waste and much of this waste was pumped into the Columbia River up until the mid-1990s.

The Plot Thickens

By the early 1990s the U.S. became aware of Canada fining Teck due to inappropriate dumping procedures involving sulfuric acid, Zinc and cadmium, as well as spills of sulfuric acid, but the U.S. refrains from lobbying fines of their own. Once there was knowledge of a spill, U.S. government agencies were supposed to notify local residents right away. However, this did not occur in relation to the Teck smelter.

Several studies conducted through the 80s and 90s showed elevated levels of mercury in fish such as trout. The most dangerous levels found in fish that many residents liked to catch and consume were usually found around the time a spill had recently occurred. Upon the conclusion of later testing, mercury levels had gone down to a reasonable level in the fish. However, it was found that bottom-dwelling fish were still showing higher than reasonable amounts of mercury in their system. Residents were not notified.

When a corporate memo was issued internally by a Teck environmental manager, Richard Dalosse, it didn’t seem very positive. The memo sent to Dalosse’s supervisors included a startling quote, “If we fail to ensure accurate monitoring of this discharge, it is possible that we could be held civilly or criminally liable.” By then Canadian regulators were already urging Teck to conduct a study regarding the Columbia River and pollution.

In 1994, Teck’s Columbia River Integrated Environmental Monitoring Program concluded its river pollution study. Findings showed a substantial amount of toxins were found south of Teck’s smelter inside of the river’s sediment. The study ended at the Canadian/U.S. border, but located just south of the border are the towns of Northport, Waneta and Washington.

It’s important to note that dumping in the river, within limits, is legal on both the American and Canadian sides of the river. However it’s become increasingly clear that Teck has had quality control issues with over dumping and spills; the last took place in 2010.

One outstanding issue residents of surrounding towns have with this information is that legally they should have been notified and never were. Much of this information has been collected thanks to the curiosity and diligence of a frustrated former resident, Jamie Paparich, whose own family members and friends suffer from various forms of IBD.

Putting the Pieces of the Story Together

On August 15 the Vancouver Sun ran an interview with Jamie Paparich and her aunt, Rose Kalamarides. Paparich a former Northport resident formed the Northport Project, which now consists of an extensive series of documents including a timeline laying out varying amounts of pollution dumped, spills, and the dates they took place.

As part of the Northport Project, Paparich performed an informal survey she hoped would catch the eye of the medical community. Results came back showing what Paparich had suspected all along, a potential IBD cluster, as well as something else. Additional smaller clusters involving certain types of cancer, as well as thyroid disease and Multiple Sclerosis; both are also inflammatory disease brought on by the immune system.

Speaking about the location of the family farm she grew up on, “It’s where the river starts to slow down and creates pools and swimming holes.” Both Paparich’s father and aunt grew up on the farm, as well. “All these kids swam in it, we irrigated with it, for decades, she added.” In the 1980s the state of Washington placed air monitors on the property to track air pollution. Results showed elevated levels of arsenic and cadmium.

Why did they do it?

One possibility could be, because the family farm is located along Mitchel Road. The very same road from the landmark farming lawsuit that took place many decades ago.

Rose Kalamarides, along with another sister, related a story to reporters about how during summertime their mother’s grocery bill was never higher than $5.00. Everything they ate came from the farm. Looking back now, they acknowledge you can’t see pollution in the head of lettuce you’re eating. And when referring to the aroma that wafted 15 miles south into Northport, Kalamarides told the Spokesman-Review, “When we were kids walking to school, we could smell it in the air.”

Now at the age of 56, Kalamarides has been dealing with ulcerative colitis for close to 30 years. Along with struggling to keep weight on and having to endure numerous blood transfusions, Kalamarides has had quite the battle with ulcerative colitis from having to have her colon removed to needing an ostomy, and now requires a catheter. As for her brother Jim (Paparich’s father), he has the disease too but is faring better.

Included in the group of people who have IBD that Kalamarides personally knows are a good friend, her third grade teacher and a childhood classmate.

Growing concerned with the amount of people she knew living with IBD, Paparich took the information she gathered from her Northport Project’s informal survey and set out to get the attention of the medical community. And that’s exactly what happened. Introducing Dr. Joshua Korzenik, director of the Crohn’s and Colitis Center at Brigham and Women’s Hospital, and the man who Paparich got to pay attention to her findings.

“10 to 15 Times More IBD Than Expected to Be Seen…”
After Paparich got the attention of Dr. Korzenik, he put together a small health study, which he hopes to expand and get funding for eventually. For now, it will be a labor of love for him and his team. The study contained 119 current and former Northport residents. The results, 17 came back with having either ulcerative colitis or Crohn’s disease.

What this means in terms of the bigger picture is that it’s a very high number – about 10 to 15 times higher than expected to be seen in a small population like Northport, said Dr. Korzenik. As for one of Dr. Korzenik’s fellow researchers, Dr. Sharyle Fowler, she said, “We should be expecting to see one or two cases for a town the size of Northport.”

There are also others in Northport with digestive tract issues, who have not officially received an IBD diagnosis at this time, like two of Clifford Ward’s children.

The End …

Through his preliminary research, Dr. Korzenik has already ruled out a genetic influence being linked to the potential Northport cluster. Yes, he believes it is a cluster. The genetic theory was discounted when results showed only a few individuals were related; like Jamie Paparich’s aunt and father.

Another thing the Harvard research team found interesting is that of the 17 people from the study confirmed to have IBD, seven of them live(d) along Mitchell Road. Yes, the very same road where Paparich’s family farm is located and area of farmland related to the landmark lawsuit.

While there is no cure for Crohn’s disease or ulcerative colitis yet, much speculation circulates around environmental triggers since increases in diagnoses started after the industrial revolution took place. It is with this reasoning that if the IBD cluster can be confirmed, Dr. Korzenik believes Northport could hold the key to finally getting much needed answers.

What a great ending this could make — Northport, the town that helped cure Crohn’s disease and ulcerative colitis.

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